Release Date: March 15, 2017
Expiration date: September 15, 2017
Estimated Time to Complete Activity: 1.0 hours
CME ACCREDITATION AND DESIGNATION
The Cardiovascular Research Foundation is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.
The Cardiovascular Research Foundation designates this activity for a maximum of 1.0 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Documentation of awarded credit is provided for participants in exchange for completed activity evaluations.
CME for MOC: Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 1.0 MOC points in the American Board of Internal Medicine’s (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider’s responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit.
OVERVIEW
During this informative webcast, listen to experts tackle the important topic of how best to revascularize patients with left main disease. Learn about data from the two main trials, EXCEL and NOBLE, in which patients with simple or moderate coronary artery disease with left main component are studied. Patients are compared randomly as either undergoing PCI or surgery.
Left main disease affects the entire system and increases morbidity due to myocardial supply. Previously the only choice was surgery, but now in the era of DES, interventional cardiology offers another choice. SYNTAX was the first study to share results. The new trials, EXCEL and NOBLE, were presented at TCT, and published in the NEJM, and the Lancet.
The EXCEL trial randomized patients in a 1:1 with either bypass surgery or DES. Conclusions of this study included treatment of patients with LMCAD and low or intermediate SYNTAX scores with CoCr-EES, resulting in similar rates of the primary endpoint of death, stroke, or MI at three years and fewer adverse events within 30 days compared to CABG. PCI should be considered an acceptable or even preferred revascularization modality for selected patients with LMCAD after heart team discussions.
The NOBLE trial took patients with left main disease and no particular SYNTAX score, but patients had 0-3 additional complex lesions. Patients were also randomized 1:1 with PCI and CABG.
This webcast provides valuable insight into both trials with a comprehensive comparison. The panel will also share insights into how their practice changed as a result of these trials.
LEARNING OBJECTIVES
After participating in this event, learners will be able to:
- Compare and contrast the differences between the NOBLE and EXCEL trials
- Identify the endpoints of each of the trials and their limitations
- Define the benefits of PCI and surgery in patients
- Discuss the changes in patient outcomes from the latest trial data
TARGET AUDIENCE
This activity is designed for interventional cardiologists, cardiac surgeons, clinical cardiologists, vascular medicine specialists, and other health care professionals.
ACTIVITY EVALUATION
Evaluation by questionnaire will address content, presentation, possible bias, and future educational needs.
DISCLOSURE STATEMENT
It is the policy of the Cardiovascular Research Foundation to ensure balance, independence, objectivity, and scientific rigor in all of its sponsored educational activities. Commercial support from industry does not influence educational content, faculty selection, and/or faculty presentations, and, therefore, does not compromise the scientific integrity of the educational activity.
Discussion of off-label product usage and/or off-label product use is made at the sole discretion of the faculty. Off-label product discussion and usage is not endorsed by the Cardiovascular Research Foundation or the conference directors of this activity.
Faculty participating in continuing medical education activities sponsored by the Cardiovascular Research Foundation are required to disclose to the activity audience any real or apparent conflicts of interest related to the content of their presentations. Faculty not complying with this policy are not permitted to participate in this activity.
FACULTY DISCLOSURE SUMMARY
KEY: (G/R) Grant Support/Research Contract (C/H/S) Consultant Fee/Honoraria/Speaker’s Bureau (E) Equity (R/I) Royalty/Intellectual Property Rights (S) Salary/Salary Support (O) Other Financial Benefit
Martin B. Leon- None
Gregg W. Stone-None
Roxana Mehran-(G/R) Abbott Vascular
Ajay J. Kirtane - (G/R) Abbott Vascular, Boston Scientific Corp., Medtronic
Planning Committee
Arielle Gelardi (Planner)
(S) Cardiovascular Research Foundation
ACTIVITY SPONSORSHIP AND SUPPORT
This program is sponsored by the Cardiovascular Research Foundation. It is supported through an educational grant from Abbott Vascular and was developed without influence from commercial supporters.
HOW TO RECEIVE CME CREDIT
To obtain CME credit for this activity, participants must review all CME information, view all presentations in their entirety, and complete the Activity Evaluation Form. If you have any questions, please contact Arielle Gelardi at agelardi@crf.org